BIO 161 Lecture Notes - Lecture 16: Endoplasmic Reticulum, Myocyte, Motor Neuron

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28 Dec 2017
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(1) motor neuron sends action potential and acetylcholine is released into synapse. (2) acetylcholine binds to its receptor (ligand-gated channels for na+) na+ enters muscle and depolarize to threshold (eps) and action potential begins on muscle membrane. (3) action potential travels along t tubulues (extension of membrane that wrap around myofibrils) (4) action potential causes ca2+ to be released from sarcoplasmic reticulum inside muscle fiber. (6) tropomyosin movement allows myosin head to bind to actin (cross bridge attachment) (1) myosin ehad swings forward pushing actin toward middle of sarcomere. (2) adp + p removed from myosin head (head forward still bound to actin) (1) atp binds to myosin head to deatch myosin from actin. (2) atp bound to myosin head = low energy conformation. (1) atp is hydrolyzed so adp + p bound to myosin head. (2) head is back = high energy conformation.

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