CEM 311 Lecture Notes - Lecture 30: Triosephosphate Isomerase, Phosphoglycerate Mutase, Phosphoglycerate Kinase

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Except: the large positive free energy is important in getting the pathway started. In the conversion of glucose to pyruvate via glycolysis, all of the following enzymes participate. Number the following enzymes 1 through 7 in the order in which they function: phosphohexose isomerase, phosphofructokinase-1, triose phosphate isomerase, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase, phosphoglycerate mutase, pyruvate kinase. Glycolysis in the erythrocyte produces pyruvate that is further metabolized to: Under anaerobic conditions, skeletal muscle generates lactate from pyruvate to: regenerate nad+ for further glycolysis. The oxidation of one mole of glucose by aerobic glycolysis yields a net of: two moles of pyruvate, two moles of nadh, and two moles of atp. An enzyme used in both glycolysis and gluconeogenesis is: Gluconeogenesis must use "bypass reactions" to circumvent three reactions in the glycolytic pathway that are highly exergonic and essentially irreversible. Reactions carried out by which three enzymes must be bypassed in the gluconeogenic pathway? hexokinase, phosphofructokinase-1, pyruvate kinase.

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