CEM 311 Lecture Notes - Lecture 48: Inverted Repeat, Transfer Rna, Ribosome
Document Summary
Rho independent terminators, also called intrinsic terminators bacuse they need no other factors to work, consist of two sequence elements: a short inverted repeat (of. ~20 nucleotides) followed by a stretch of about eight a:t base pairs. These elements do not affect the polymerase until they have been transcribed - that is, they function in the rna rather than in the dna. When polymerase transcribes an inverted repeat sequence, the resulting rna can form a stem-loop structure (often called a "hairpin") by base pairing with itself. Formation of the hairpin causes termination by disrupting the elongation complex. mrna. Messenger rna (mrna) is a large family of rna molecules that convey genetic information from dna to the ribosome, where they specify the amino acid sequence of the protein products of gene expression. Following transcription of primary transcript mrna (pre-mrna) by rna polymerase, processed, mature mrna is translated into a polymer of amino acids (protein).
