PSYC 3406 Lecture 12: Lecture 12 - Schizophrenia
What genotype of serotonin 2A receptor is associated with anorexia?
● AA
Schizophrenia
Definition
● The schizophrenic disorders are characterized by distortions of thinking and perceptions
and affects that are inappropriate or blunted
● Clear consciousness and intellectual capacity are usually maintained although certain
cognitive deficits may evolve over time
● Include
○ Thought echo
■ Same thought over and over again
○ Thought insertion or withdrawal
■ Thoughts completed and removed at random
○ Thought broadcasting
■ Audible hallucinations
■ Broadcast thoughts into other beings
● Thinks something (inanimate object, animal, god) is talking to
them
■ Thinking others can hear your thoughts
○ Delusional perception and delusions of control
○ Influence or passivity
○ Hallucinatory voices commenting or discussing the patient in the third person
○ Thought disorders and negative symptoms
● Occurs with regular frequency nearly everywhere in the world in 1% of the population
(mostly around 16-25yo)
● Defined by
○ A group of characteristic positive and negative symptoms
○ Deterioration in social, occupational, interpersonal relationships
○ Continuous signs of the disturbance for at least 6 months
History
● Emil Kraepelin
○ Illness develops relatively early in life
○ Deteriorating and chronic
○ Dementia but didn’t have any organic changes in the brain (dementia praecox)
● Eugen Bleuler
○ Renamed Kraepelin’s dementia as schizophrenia (1911)
○ Cognitive impairment in illness named as splitting of mind
● Kurt Schneider
○ Emphasized role of psychotic symptoms as hallucinations, delusions
○ “First rank symptoms” (hallucinations, delusions)
4A (Bleuler)
● Maintained 4 symptoms necessary
Document Summary
The schizophrenic disorders are characterized by distortions of thinking and perceptions and affects that are inappropriate or blunted. Clear consciousness and intellectual capacity are usually maintained although certain cognitive deficits may evolve over time. Thinks something (inanimate object, animal, god) is talking to them. Hallucinatory voices commenting or discussing the patient in the third person. Occurs with regular frequency nearly everywhere in the world in 1% of the population (mostly around 16-25yo) A group of characteristic positive and negative symptoms. Continuous signs of the disturbance for at least 6 months. Dementia but didn"t have any organic changes in the brain (dementia praecox) Cognitive impairment in illness named as splitting of mind. Emphasized role of psychotic symptoms as hallucinations, delusions. Groups of symptoms called four as and bleuler though they were primary for diagnosis. Other known symptoms (hallucinations, delusions) are called secondary symptoms because they could be seen in any psychotic disease which are caused by other factors.