PSYC 3406 Lecture 12: Lecture 12 - Schizophrenia

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What genotype of serotonin 2A receptor is associated with anorexia?
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Schizophrenia
Definition
The schizophrenic disorders are characterized by distortions of thinking and perceptions
and affects that are inappropriate or blunted
Clear consciousness and intellectual capacity are usually maintained although certain
cognitive deficits may evolve over time
Include
Thought echo
Same thought over and over again
Thought insertion or withdrawal
Thoughts completed and removed at random
Thought broadcasting
Audible hallucinations
Broadcast thoughts into other beings
Thinks something (inanimate object, animal, god) is talking to
them
Thinking others can hear your thoughts
Delusional perception and delusions of control
Influence or passivity
Hallucinatory voices commenting or discussing the patient in the third person
Thought disorders and negative symptoms
Occurs with regular frequency nearly everywhere in the world in 1% of the population
(mostly around 16-25yo)
Defined by
A group of characteristic positive and negative symptoms
Deterioration in social, occupational, interpersonal relationships
Continuous signs of the disturbance for at least 6 months
History
Emil Kraepelin
Illness develops relatively early in life
Deteriorating and chronic
Dementia but didn’t have any organic changes in the brain (dementia praecox)
Eugen Bleuler
Renamed Kraepelin’s dementia as schizophrenia (1911)
Cognitive impairment in illness named as splitting of mind
Kurt Schneider
Emphasized role of psychotic symptoms as hallucinations, delusions
“First rank symptoms” (hallucinations, delusions)
4A (Bleuler)
Maintained 4 symptoms necessary
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Document Summary

The schizophrenic disorders are characterized by distortions of thinking and perceptions and affects that are inappropriate or blunted. Clear consciousness and intellectual capacity are usually maintained although certain cognitive deficits may evolve over time. Thinks something (inanimate object, animal, god) is talking to them. Hallucinatory voices commenting or discussing the patient in the third person. Occurs with regular frequency nearly everywhere in the world in 1% of the population (mostly around 16-25yo) A group of characteristic positive and negative symptoms. Continuous signs of the disturbance for at least 6 months. Dementia but didn"t have any organic changes in the brain (dementia praecox) Cognitive impairment in illness named as splitting of mind. Emphasized role of psychotic symptoms as hallucinations, delusions. Groups of symptoms called four as and bleuler though they were primary for diagnosis. Other known symptoms (hallucinations, delusions) are called secondary symptoms because they could be seen in any psychotic disease which are caused by other factors.

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