EEOB 2520 Lecture Notes - Lecture 2: Lipid Bilayer, Osmosis, Mitochondrion
14 Feb 2017
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Components fluid mosaic: constantly moving different pieces. Polar heads with 2 non polar tails = amphipathic. Increases barrier to small polar compounds (fills in gaps in bilayer) Allows for controlled bending of plasma membrane. Protein: ~1:50 with phospholipids but 1/2 of plasma membrane mass. Most transmembrane (goes across the membrane); all not reliable. Glycocalyx: (sugar component) branched carb chains on extracellular fluid side (outside) Forces movement through the cell, aka transcellular. No passage between cells, selective passage through cells. Eq 1: atp < > adp + pl + energy. Adp + xp < > atp + x (x = substrate) Energy input to transfer unbound pi to adp. Breakdown sugar to get atp out of it. Cytosol = 10 enzymatic (nz) reactions > dependent on proteins. Alternative: derivatives from amino acids and lipids. Net production = 28-34 atp, h2o*, recycling.
