PSYCH 3313 Lecture Notes - Lecture 8: Dopamine Beta-Hydroxylase, Aromatic L-Amino Acid Decarboxylase, Monoamine Oxidase
21 Sep 2016
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Act on neurons in immediate vicinity: neuromodulators and neurohormones. Acetylcholine (ach: role in peripheral nervous system. Somatic: neuromuscular junction: role in central nervous system. Projections from basal forebrain to hippocampus and amygdala; septal area; brainstem: behavior(s) Autonomic function, movement, learning and memory: clinical conditions. Reuptake or broken down by enzyme acetylcholinesterase (ache: cholinergic projections of the human brain. Cholinergic nuclei of the pons and midbrain: nicotinic ach receptor. Serotonin is synthesized from tryptophan: histamine, catecholamine synthesis. Dopamine (da: role in peripheral nervous system. Neuromodulator for other neurotransmitters: role in central nervous system. Ventral tegmental area (vta) hippocampus, amygdala, nucleus accumbens and frontal lobe: behavior(s) Movement control, reinforcement and planning: clinical conditions. Parkinson"s disease, schizophrenia and drug abuse: synthesis. F. 1. d1 and d5 = stimulatory g-protein coupled receptors. F. 2. d2, d3 and d4 = inhibitory g-protein coupled receptors: degradation. Enzymes monoamine oxidase (mao), catechol-o-methyl transferase (comt) and aldehyde dehydrogenase acting in sequence to break down dopamine: dopaminergic (da) projections of the human brain.
