PSYCH 3313 Lecture Notes - Lecture 4: Camillo Golgi, Schwann Cell, Neuron Doctrine

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The battle of the doctrines: reticularist doctrine (camillo golgi, neuron doctrine (santiago ramon y cajal) What are the cells of the nervous system: glia. Information processing and communication: glue , non-neural, outnumber neurons 9x, physical and functional support functions to neurons, may have many clinical implications. Many functions of astrocytes: symmetrical star shape, structural matrix support for neurons, contribute to blood-brain barrier: neurovascular units. Myelin sheath = wrappers around axons that act as insulators of neuron"s signal. Microglia: sense molecules associated with cellular damage and digest the debris, first and main form of active immune defense in cns. Destroy infectious/toxic agent: 10 15% of all cells in brain, resting vs. activated state. The cell body/soma: cytoplasm: cytosol and organelles, nucleus: contained in nuclear envelope. Assembly of proteins from 20 amino acids: provides metabolic (energy) and synthetic (protein) support, acts to gate information flow to and from other neurons. Integrates signals from many sources of input (integration zone)

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