MICR 2123 Lecture Notes - Lecture 17: Opsonin, Clonal Selection, Histocompatibility

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31 Mar 2017
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Retains memory of those antigens: faster response if exposed a second time. Lymphocytes are cells that mediate adaptive immunity: b cells humoral immunity, t cells both types. Antigen: (immunogen) any molecule that will, when introduced to a person, elicit the synthesis of antibodies that specifically bind the antigen. Immune system does not recognize the whole microbe, but innumerable tiny pieces of it: each small segment of an antigen that elicits an immune response is called an epitope. Immunogenicity: measures the effectiveness by which an antigen elicits an immune response: proteins = most effective antigens (more immunogenic than other types of molecules like. Lps or lipids: immunological specificity: antibody made to one epitope will not bind to other epitopes. Ex: antibody to cowpox virus will bind to a similar epitope on smallpox virus (used for vaccination) Immunogens: antigens that can elicit antibody production by themselves. Haptens: small molecules that are not immunogenic on their own.

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