SSE121 Lecture Notes - Lecture 1: Diagnostic And Statistical Manual Of Mental Disorders, Pharmacology, Nicotine
2 May 2020
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Document Summary
Clinical pharmacology and clinical epidemiology and clinical epidemiology of. Pharmacology is "the study of the impact on living organisms of chemical compounds" Many knowledge in pharmacology is derived from animal research because of the obvious risks. When tested on non-humans, the dosage of a drug may have no effect but may have a major impact on humans. 2)thousands of subjects are working in animal studies. Millions of people are involved in active drug use so that relatively small issues with larger scale use can be quite important. 3)non-humans can not predict any cognitive, behavioral, and social effects of substances. Tolerance is a disorder in which "repeated doses of the same amount of medication are diminishingly efficient and progressively greater doses are needed to achieve a desired effect" Tolerance evolves through groups of drugs to varying degrees. For example - users of opioids and amphetamines may develop significant tolerance. Users of alcohol and nicotine may develop tolerance to a lesser degree.
