BIOSC 1250 Lecture Notes - Lecture 14: Vascular Resistance, Vascular Smooth Muscle, Cardiac Output
Document Summary
Regulation of regional blood flow; overall cardiovascular regulation. Now let"s turn our attention to distribution of blood flow to different tissues. First, remember that p = f: r, which in the case of the cardiovascular system is mean arterial pressure = cardiac output, total peripheral resistance. 5l/min is flowing through systemic tissues at rest, but all tissues don"t have equal perfusion needs. (slide 2) some tissues have relatively high blood flow (expressed per gram tissue) because they have relatively high energy needs (brain, heart). Others have high blood flow because they have important functions in regulating blood composition (kidneys, liver). Other tissues at rest have low energy needs (e. g. , muscle, skin, bone) and low blood flow. [what mechanism might match "tissue need" to flow?] The relative resistances of the arterioles in the different tissues. (slide 3) Note that this distribution is subject to regulation, and can change markedly.
