HRS 1017 Lecture Notes - Lecture 9: False Positives And False Negatives, Overdiagnosis, Scientific Method
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Finding someone who is true positive but will never progress through the natural history of the disease. Being treated when they will not benefit from it. Getting all the risks of the treatment, but no benefits. Examines causal (etiologic) hypotheses regarding the association between exposures and health conditions or health outcomes. The foundation is to look to link to exposure and disease. Research is conducted following a coordinated plan using the scientific method. Study designs are a part of this plan and direct how the investigation is conducted. Suspicion that a factor (exposure) may influence occurrence of disease. A. formulate a hypothesis about the relationship between the exposure and disease. Identify a specific study design to guide the research. C. conduct research studies to identify if the hypothesis is correct or not. A study design provides a plan or protocol that directs how a research investigation should be conducted.