BIOL 12100 Lecture Notes - Lecture 7: Silent Mutation, Hemoglobin, Start Codon
24 Feb 2015
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2 chains of alternating sugar and phosphate. Since a - t and g - c. The sequence of nucleotides aon 1 stranded specific to other. Disruption - mixed old and new dna in 1 strand. Bands at the middle and top appeared. Miscopying dna polymerase 1 in 10^6 bp. Error rate = one in 10 billion nucleotides (10^10) They make 3 bases (codon) for 4^3 (64 combination) Over 99. 5% of our nucleotides are identical, but there are 3 million positions where there is variation(snps) Companies will compare your snps with people with certain diseases and assess your probability of getting hundreds of diseases. Not very useful yet - biological and clinical meaning of snps largely unknown. G. i. n. a. (genetic information nondiscrimination act of 2008) There are genetic tests for more than 1500 conditions. Fear of misuse of genetic information limit test ues. Law protects consumers from discrimination by health insurers and employees on basis of genetic information.
