EAR-20 Lecture Notes - Lecture 12: Molecular-Weight Size Marker, Genetic Recombination, Mitosis

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4 Dec 2020
School
Course
Professor
Keenan Lieu
Spring 2020
Child Growth and Development
Cell Division and Chromosome Duplication
Each of s began life as a single cell created when a sperm cell, normally containing 23
chromosomes from the father, united with an ovum (egg), normally containing an
additional 23 chromosomes from the mother
Zygote: fertilized egg cell
Nearly ever one of the millions of different cells in the newborn, whether specialized for
bone or skin, heart or brain, or in some other way, contains the same genetic blueprint
established in the initial zygote
Mitosis: process of cell division that takes place In most ells of the human body and
results in a full complement of identical material in the 46 chromosomes in each cell
During mitosis, genetic material in the nucleus of the cell is reproduced such that
a full complement of DNA becomes available to each new cell
Before cell division occurs, the chemical bonds linking the nucleotides that
forms the DNA ladder weaken
Pairs of nucleotides separate as though they are being unzipped from each other
At the same time additional nucleotides are manufactured in the cell and attach
to the separated nucleotides (each nucleotide can combine with only one other
type)
The two newly formed strands of DNA are normally rebuilt in exactly their
original sequence
The two newly formed copies of DNA eventually separate completely so that
one becomes a member of each of the two new daughter cells
Meiosis: process of cell division that forms the gametes; normally results in 23
chromosomes in each human egg and sperm cell rather than the full complement of 46
In the first stage, each of the 46 chromosomes begins to replicate in much the
same way as mitosis begins
Before identical replicas split apart, the cell divides, so that each daughter cell
receives only one chromosome from each of the 23 pairs
In the second stage, the replicas of the 23 chromosomes completely separate, and
the cell divides once more, each cell again receiving one of the replicas
Four cells are produced, each with 23 chromosomes
Crossing over: process during the first stage of meiosis when genetic material is
exchanged between autosomes
The potential for genetic variability
The process of genetic recombination makes it virtually impossible for two
individuals to have the same genetic makeup, even siblings, unless the two are
identical
Gene Expression
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Document Summary

Each of s began life as a single cell created when a sperm cell, normally containing 23 chromosomes from the father, united with an ovum (egg), normally containing an additional 23 chromosomes from the mother. Nearly ever one of the millions of different cells in the newborn, whether specialized for bone or skin, heart or brain, or in some other way, contains the same genetic blueprint established in the initial zygote. Mitosis: process of cell division that takes place in most ells of the human body and results in a full complement of identical material in the 46 chromosomes in each cell. During mitosis, genetic material in the nucleus of the cell is reproduced such that a full complement of dna becomes available to each new cell. Before cell division occurs, the chemical bonds linking the nucleotides that forms the dna ladder weaken. Pairs of nucleotides separate as though they are being unzipped from each other.

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