BIOL 01203 Lecture Notes - Lecture 12: Integrin, Laminin, Fibronectin
23 Jul 2018
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Document Summary
Distinguish between the glycocalyx, a basement membrane, and the extracellular matrix of cartilage tissue. glycocalyx surrounds the cell basement membrane surrounds muscle and fat cells. Extracellular matrix of cartilage- role in cell shape and activities-- secreted by cells: contrast the roles of collagen and proteoglycans in the extracellular space. Collagens are fibrous protein that gives the extracellular metric the capacity to resist pulling forces. Collagen plays a key role in giving tissues strength and structural integrity. Proteoglycans consists of protein and glycosaminoglycan and serves as an amorphous packing material that fills the extracellular matrix. Fibronectin and laminin contribute to the embryonic development. Cleft formation and branching is entirely abolished as a result of the inactivation of the fibronectin molecule. Laminin plays a critical role in the migration of primordial germ cells: list a few of the functions of the extracellular matrix in animal tissues.
