11:067:327 Lecture 4: Lecture 4_ Male Reproductive System

• School: Rutgers University
• Department: Animal Science
• Course: 11:067:327
• Professor: C Bagnell

Document Summary

Immune privilege: haploid sperm (n) are considered foreign to the immune system. Blood-testes barrier: prevents autoimmune destruction of developing haploid germ cells in the tubule (a) formed by: peritubular myoid cells, sertoli cells junctional complexes (b) develops at puberty, blocking high. Mw substances (b) somatic cells (c) germ cells. Post-meiotic: spermatids (n) (i) (ii) meiotic: primary (n), secondary (2), and spermatocytes (2n) (iii) mitotic: spermatogonium (2n) (d) blood testes barrier (i) Bind fsh and testosterone; analogous to ovarian granulosa cells. Large number of sertoli cells=large number of sperm (b) sertoli cells produce. Sulfated glycoprotein 1 & 2: fertility acquisition; facilitate cell/fluid movement. Transferrin: iron transport protein required for (iii) spermatogenesis. Heat transfer to the spermatic vein which returns cool (33 c) blood to the body (4) cremaster muscle: pumps blood through ppp (a) function: (i) Primary skeletal muscle support for the testes (ii)