11:067:327 Lecture Notes - Lecture 7: Ion Channel, Cell Growth, Gene Expression
29 Dec 2019
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Less than a teaspoon full in the body. 1/2): a short half life is important (1) secretion- response (2) response- degradation, bind to specific receptors, nuclear and membrane receptors, regulate intracellular biochemical reactions, gene expression, signalling pathways, cell growth d) Ion channel function: classified according to: (table 5-2, source, mode of action, biochemical classification. Sometimes it can create a tumor from increased amount of prolactin. It turns out it acts on connective tissue of the reproductive system by softening it, like the cervix for partunition. (i) (ii) (iii) Relaxin knockout mouse: quicker parturition would be assumed, but it didn"t do anything because you don"t need relaxin for mice birth since they are so small and can fit through the birth canal. If you do knockout the relaxin, when the mice get older their organs harden due to fibrosis and no tissue rebuilding. The moms could get pregnant, but the knockout females never developed nipples.
