11:067:330 Lecture Notes - Lecture 15: Bone Resorption, Milk Fever, Dicalcium Phosphate

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Vitamins and minerals work together in body in a coordinated fashion. Ex: calcium, phosphorus, vit d (acts as hormone) work together for growth and development. Structural nutrients for bone and tooth formation. Calcium also critical for nerve transmission, muscle contraction, and blood clotting. Phosphorus needed in e metabolism for synthesis of atp, backbone of rna/dna, and bilayer. Dietary sources: milk and animal byproducts (fishmeal, bonemeal) Green, leafy crops (alfalfa) high in ca2+, cereal grains high in p. Dicalcium phosphate added when both calcium and phosphorus needed. Ground limestone (caco3) used as source of calcium. Key regulator of calcium and phosphorus levels in blood. A steroid derived from cholesterol; two active forms (d2 and d3) Both forms produced from provitamins, commonly found in feeds and activated in body. Provitamin for d3 = cholecalciferol (from diet or made by skin from 7-dehydrocholesterol. Cholecalciferol undergoes two-step activation process: kidneys produce final active d3.

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