01:119:115 Lecture Notes - Lecture 8: Chemiosmosis, Glut1, Pyruvic Acid

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Lecture 8 - cellular respiration: introduction to cell respiration, energy flow. Chemical e in bonds nutrients chemical e in atp e used for cell work: overview of eukaryotic respiration. C6h12o6 + 6o2 6co2 + 6h2o + e (in atp) Redox reactions transfer e- from sugar to o2. It is catabolic & exergonic g is -686kcal/mol. Follow the h in the above reaction. 4 stages: glycolysis, pyruvate oxidation, citric acid cycle (kreb"s cycle, oxidative phosphorylation. Converts 1 glucose into 2 pyruvate and 2 net gain of atp. Glucose enters cell: (mammals) via facilitated diffusion by glut1. 2 g3p 2 pyruvate, 2 nadh, 4 atp. Pyruvate must be modified to enter into mitochondria. Converts pyruvate to acetyl coa (to start krebs cycle: outer mitochondrial membrane - diffusion through small pores, inner mitochondrial membrane - carrier protein needs e. Builds a nadh: the citric acid cycle (cac): krebs cycle. Break down acetyl coa as efficiently as possible.

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