01:119:115 Lecture Notes - Lecture 13: Thyroid, Posterior Pituitary, Anterior Pituitary

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Lecture 12: endocrine system ii: organization of regulatory pathways, simple endocrine pathway. Hormone travels via bloodstream >interacts with target cell. Ex: ph in duodenum: simple neuroendocrine pathway. Stimulates neurosecretory cell(rather than endocrine cell) >secretes neurohormones. Ex: milk release during nursing (also a rare example of pfl) Negative feedback: way more common, a -stimulates ->b, b inhibits ->a. Larva grows in discrete stages, must molt periodically-shed exoskeleton, secrete new one. Endocrine pathway begins in larval brain: endocrine pathway. Ptth signals prothoracic gland to make ecdysteroid. Produced in bursts-each burst triggers a molt. Also induces metamorphosis-change in form in adult. Secreted by corpora allot (pair of endocrine glands) Key regulatory structure-directly or indirectly controls most hormone activity. Connected directly to pituitary gland by portal vessels: 2 modes of action, produces releasing hormones (rh) and inhibiting hormones (ih, produces antidiuretic hormone(adh) and oxytocin. Stimulates or inhibits release of specific hormones from ap. 2 lobes in humans: posterior pituitary.

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