01:119:115 Lecture Notes - Lecture 4: Protocell, Proterozoic, Cell Nucleus

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Chemical evolution: fossil evidence - 1st microorganisms are from 3. 5 billion years ago, hypothesis: life developed from nonliving matter. Abiotic synthesis - spontaneous formation of small organic molecules. Organic macromolecules - came from 2 small organic mol. combining (proteins and nucleic acid) B. 3. b) droplets with enclosing membrane maintain separate internal and external environment. Origin of self-replicating molecules led to inheritance: requirements for chemical evolution to occur: Lack of oxygen - if o2 is present, it will oxidize bonds aka break bonds; need high reduction aka making of bonds. Source of energy - violent thunderstorms, lightning, volcanoes, etc. Chemical building blocks - h2o, inorganic molecules, atmosphere (gases) Formation of organic molecule: small organic molecules. Oparin-haldane hypothesis: conditions of early earth favored spontaneous organic molecule formation. Suggested that organic molecules accumulated in oceans sea of organic soup probiotic soup hypothesis . Miller-urey experiment: life created from nonliving things (a. 1. c. 1) created a closed system to simulate earth; had.

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