01:119:116 Lecture Notes - Lecture 21: Sarcomere, Multinucleate, Cierva C.4
21 Apr 2016
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Lecture 21: musculoskeletal system: muscle - contractile tissues movement, motor output mechanical force, locomotion, manipulation of environment, blood circulation, feeding, peristalsis (moving food through digestive system) Ii: 3 types of muscles - skeletal, smooth, cardiac. Attached to bones via tendons- cords of connective tissue. Tropomyosin blocks site, troponin complex helps block (b) thick filaments (i) (ii) (iii) Each has head and tail, heads stick out. If strong enough ap in muscle fiber (i) Problem: muscle fibers are huge (a) axons are narrow, ap spreads easily- not so in muscle fibers (ii) Solution: t-tubules (a) ap travels along pm t tubules sr . Only enough for a few seconds of activity present. Other types of muscles: cardiac muscles, walls of heart, striated, branched cells, unique functionality- contract simultaneously, independently. Intercalated discs: smooth muscle, wall of digestive tract, bladder, uterus, blood vessels, not attached to bone, not striated, no t tubules, not well developed sr, less efficient, slow contractions, slow relaxation.
