01:146:295 Lecture Notes - Lecture 16: Circadian Rhythm, Lower Motor Neuron, Sleep Paralysis

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16: sleep and circadian rhythms: force you to lie still to consume less energy at night, hide from predators, brain maintenance: clean out waste products. Information processing (memory): weaken synaptic connections that were strengthened during waking. Brain maintenance: sleep clears the brain of toxic metabolic products: when awake, csf doesn"t penetrate into the brain too deep, when asleep, neuron size shrinks opens up more space between neurons . Csf can go deeper into brain tissue cleans out brain tissue. Space around arteries in brain create by astrocytes create a channel around arteries and veins. During night, there is an increase in byproducts, chemicals, and waste molecules (such as beta-amyloid) in the csf. Sleep states: defined by electroencephalogram (eeg): records sleep patterns. Ion currents generate small voltage differences around the dendrites. Electrodes on the outside ca nnot pick up activity from individual nerve cells, but can pick up average activity in the brain: eeg rhythms during sleep and awake.

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