01:146:328 Lecture Notes - Lecture 15: Wuchereria Bancrofti, Loa Loa, Microfilaria
Document Summary
Nematodes filarial: filarial filaroidea, superfamily filaroidea, wuchereria bancrofti. Live in the blood or tissues no gi tract. Unsheathed tissue-dwelling spp: survive for many years, ingested by vector during a blood meal, periodicity, mf in peripheral blood only at certain times of the day, peripheral blood blood at the surface of the body, ex. Wuchereria bancrofti: maximum number of mf between 10 pm and 2 am, the vector is a night feeding mosquito, during the day the mf stay in the blood vessels of the deep tissue (lungs) Evolutionary advantage: increases chance of mf getting ingested by a suitable vector. Cause of periodicity changes in host during sleeping: decrease in body temperature, increase in body acidity, decrease in excretion of water by kidneys, life cycle of filarial worms figure 17. 1, microfilaria transmission stage. Adult worms: live in the lymphatic ducts in the lower half of the body, sexual dimorphism, female: 8-10 cm, male: 40 mm.