01:146:328 Lecture Notes - Lecture 23: Plasmodium Ovale, Plasmodium, Salivary Gland
Document Summary
To get started right away, just tap any placeholder text (such as this) and start typing: characteristics. Apical complex: rhoptries and micronemes, secretory organelles, penetrate host cells, conoid and subpellicular microtubules, structural. Complex life cycles: plasmodium, malaria, ~ 200 million cases of malaria. 4 species that infect humans: plasmodium vivax, plasmodium ovale, plasmodium malariae, plasmodium falci oarum, life cycle, overview. Transmission stage to the mosquito: vertebrate phase of life cycle. Infected female anopheles spp mosquito takes blood meal. Injects salivary gland secretions into capillary to prevent clotting. Circumsporozoite protein on surface of sporozoite binds specifically to receptors that are on. Apical complex secretions allow parasite to get into hepatocyte. Metamorphosis trophozoite (feeding stage) hepatocytes (liver cells: feeds on cytoplasm, after 1 week mature trophozoite. Begins schizony: asexual reproduction, nuclear division numerous daughter nuclei formed, = schizont, = cryptozoite, cytoplasm divides, merozoites are produced. Initial interaction between merozoite and rbc is random.