01:146:356 Lecture Notes - Lecture 10: Cerebrospinal Fluid, Paracetamol, Neuroglia

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Galen(aelius or cladius) of pergamon, the gladiators of the high priest of asia, and the neurogenic control of respiration. Injury around cervical vertebrae c-3 to c-5 - lost control of his respiration for a period of time. Aelius galenus or claudius galenus ad 129-200, ad 157/161, physician/surgeon to the gladiators. Discovered oftentimes that if a gladiator had a neck injury, if low in the cervical vertebrae like c7 to the part of thoracic vertabrae than the gladiator was paralyzed but able to breathe spontaneously. If it was in c1-c4 than the gladiator couldn"t breathe and died. Tried to reproduce it on experimental animals, high cervical incision --> lead to cessation of breathing. Correctly reasoned that there must be information coming from brain stem that must pass through cervical column to cause respiration. Find the source of eupnic - normal or true respiration.

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