01:377:213 Lecture Notes - Lecture 4: Whole Blood, Blood Plasma, Oxygen Saturation

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13 Mar 2018
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Triglyceride (1) fibrinogen (largest of the plasma proteins) (a) involved in blood clotting processes (b) converts to fibrin to form a clot (i) Fibrin is the basic framework of a blood clot (c) blood plasma with clotting proteins removed is called serum (d) fibrinogen molecules interact forming large insoluble strands of fibrin. Orientation and superficial anatomy of the heart: the heart lies slightly to the left of the midsagittal plane, located in the mediastinum, the base is the superior border of the heart. Begins at the origins of vessels and atri: the apex is the inferior portion of the heart. Extrinsic regulation of heart rate and circulation: changes in heart rate occur rapidly through nerves that directly supply the myocardium and chemical messengers that circulate in blood. Parasympathetic influence: when stimulated, parasympathetic neurons release acetylcholine, which retards the rate of sinus discharge to slow heart rate (bradycardia).

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