01:447:380 Lecture 15: Linkage, Recombination, and gene mapping
Document Summary
A gamete may contain recombinant or nonrecombinant chromosomes. Mendel"s law of independent assortment assumes that the four possible allele combinations (tb, tb, tb, tb) are all equally likely. Only happens when two genes lie far apart. Rf = something you measure in a whole population. The alleles of genes on different chromosomes assort independently. Two chromosome pairs can align in two different orientations during metaphase i. Does work when genes are one two different chromosomes. Mendel"s law of independent assortment assumes that the four possible allele combinations (tb, tb, tb, Closer gene lie to each other on arm ,the less freq the recom break point will happen. Independent assortment only occurs for genes that lie at a distance from each other. *depend on distance and whether they are close to telomere or centromere on that arm. Gene a and gene b are said to be genetically linked.