01:447:380 Lecture 8: lecture 8
24 Jul 2016
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~bacteria don"t have telomeres because it"s a circular chromosome duh. ~what unwinds dna topoisomerase etymology of this word same molecule but different structure. ~dna needs to be held open for a while, done by the ssb proteins. ~polymerase binds first at the origin of replication, opening of dna by helicase and topoisomerase happens on both sides of the origin of rep. ~diff types of polymerases replicate different types of dna. ~there is one phosphate in between bases on a strand. ~3" of a strand is complementary to 5". ~polymerase cannot start replication on just an empty open strand. ~ primase makes a little rna primer complimentary to original strand, polymerase comes in and continues off the primer.
