33:630:363 Lecture Notes - Lecture 4: Phosphocreatine, Creatinine, Gout
24 Apr 2020
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Document Summary
Nitrogen-containing compounds (urea, ammonia, uric acid, creatinine) H+, na+, k+, cl- also must be dealt with. Urea: ammonia = end product of protein breakdown, very toxic to tells, combines with co2 to form urea, less toxic, but still needs to be removed (by kidneys) Uric acid: end product of nucleic acid (dna/rna) breakdown, toxic to tells, limited solubility in blood, if too much, precipitates out gout. Creatinine: from creatine phosphate breakdown, maintains fluid balance in the body. Monitors and controls blood ph: secretes h, reabsorbs bicarbonate, produce erythropoietin (kidneys) Erythropoietin enzyme produced when oxygen in blood is low: stimulates rbc production in response, transform vitamin d into its active form. Promotes absorption and use of calcium and phosphorus: removes some foreign compounds. The urinary system"s main function is to regulate the volume, pressure, and composition of the blood. The organs of the urinary system: 2 kidneys. Structure: fist-sized, reddish, bean shaped organs in abdominal cavity.
