11:709:364 Lecture Notes - Lecture 11: Acetyl-Coa, Protein Catabolism, Cardiac Output
Document Summary
To survive, the body needs energy first from glucose via glycogen reserves which enters glycolysis. Once glucose is used body will perform gluconeogenesis and use non- Cho sources of glucose from: protein: the carbon structures of amino acids (keto-acids, fat: glycerol will convert to acetyl coa, lactate: is a byproduct of pyruvate and will circulate in liver. Increased catabolism of protein/amino acids occurs: the endpoint of amino acid metabolism keto acids and nh3. Carbon structures may be recycled for other purposes (lactate: lactate cannot convert to glucose so it travels back/forth from liver to muscles. Ebb phase (24 to 48 hours: no nutrition support, decreased, cardiac output, o2 consumption, body temperature, blood pressure, metabolic rate, insulin. Flow phase (7 to 14 days: nutrition support imperative, increased, cardiac output, oxygen consumption, body temperature, energy expenditure, protein catabolism, glucose production, free fatty acid release, catecholamine.