11:709:364 Lecture Notes - Lecture 11: Acetyl-Coa, Protein Catabolism, Cardiac Output

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To survive, the body needs energy first from glucose via glycogen reserves which enters glycolysis. Once glucose is used body will perform gluconeogenesis and use non- Cho sources of glucose from: protein: the carbon structures of amino acids (keto-acids, fat: glycerol will convert to acetyl coa, lactate: is a byproduct of pyruvate and will circulate in liver. Increased catabolism of protein/amino acids occurs: the endpoint of amino acid metabolism keto acids and nh3. Carbon structures may be recycled for other purposes (lactate: lactate cannot convert to glucose so it travels back/forth from liver to muscles. Ebb phase (24 to 48 hours: no nutrition support, decreased, cardiac output, o2 consumption, body temperature, blood pressure, metabolic rate, insulin. Flow phase (7 to 14 days: nutrition support imperative, increased, cardiac output, oxygen consumption, body temperature, energy expenditure, protein catabolism, glucose production, free fatty acid release, catecholamine.

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