01:830:101 Lecture Notes - Lecture 4: Institutional Review Board, Syphilis, Random Assignment
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Field experiment: use rare opportunities for random assignment in natural settings (e. g. some classrooms) Natural experiment: quasi-experiment, compare differences in treatment that already exist (e. g. abusive families, gender, groups chosen to match characteristics as much as possible. Ethics horror stories or the reason we have ethics safeguards: tuskegee study (1932 to 1972) African american men living in rural alabama diagnosed with syphilis. U. s. public health service never informed, or treated, the men. Merely studied the course of the disease: 28 men died of syphilis, 100 of related complications, 40 wives were infected, 19 children were born with it. In 1997, president clinton offered a formal apology. Willowbrook: children admitted to institution if parents consented to hepatitis experimentation. Radiation of 19 mentally impaired boys, through milk & food. Explanation of what is about to happen. More stringent protection of those who are incapable in some way: children.