ENS 333 Lecture Notes - Lecture 5: Coronary Artery Disease, Hmg-Coa Reductase, Stenosis
12 Jan 2017
School
Department
Course
Professor
Document Summary
Stenotic lesions: very few of these lesions, thick cap smooth muscle that covers the lesion itself, less dangerous than non-stenotic lesions. Non-stenotic lesions: there are many of these types of lesions, thin cap can rupture and form a clot. Can stop blood flow: cannot be seen with contrast dye. Spect = single photon emission computed topography. Vla = vertical long axis: slices the heart along its longest axis (tip comes to the apex) Sa = short axis: slice off the apex. Use a radioisotope and injects it: add a tissue-specific ligand and look at localized views of perfusion, bright colors = higher levels of perfusion, dark colors = lower levels of perfusion. Ischemic heart disease coronary calcium prognosis. Score is based on the intensity of the calcium. Low calcium score = good survival rates. Higher calcium score = low survival rates. People with scores over 400 are ~5x more likely to die.
