BIOL 243 Lecture Notes - Lecture 4: Cell Migration, Lipoprotein, Endosome

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2 types: active transport, vesicular transport. Both require atp to move solutes across plasma membrane bc: solute too large for channels, solute not lipid soluble, solute not able to move down concentration gradient. Requires carrier proteins (solute pumps: bind specifically and reversibly w/ substance. Moves solutes against concentration gradient: requires energy. Requires energy directly from atp hydrolysis: secondary active transport. Requires energy indirectly from ionic gradients created by primary active transport. Energy from hydrolysis of atp causes shape change in transport protein that. Involved in primary and secondary active transport of nutrients and ions. Na and k channels allow slow leakage down conc gradients. Na and k pump works as an antiporter, but it"s not: pumps against na and k gradients to maintain high intracellular k conc. and high extracellular na conc cellular volume muscle and nerve tissues. Uses up to 1/5 of the cell"s energy. Helps maintain resting potential, effect transport, and regulate.

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