SCI 1000C Lecture Notes - Lecture 19: National Cancer Institute, Salicin, Paracetamol

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Medicinal plants: 5000 years of documented history. But had a much older history from archeological finds: sick people looked around for a cure. Plants (abundant, great varieties: trial and error approach, medicinal doctors were botanists. Secondary plant products as medicine: e(cid:272)o(cid:374)dary (cid:272)o(cid:373)pou(cid:374)ds are (cid:272)he(cid:373)i(cid:272)als pla(cid:374)ts produ(cid:272)e (cid:271)ut do(cid:374)"t (cid:374)eed, many are produced to protect the plant from being eaten, they are the source of many useful compounds, spices, essential oils in herbs, medicines. Dosage effects: small and appropriate dosage: good medicine, large dosage: poisonous, narcotic, addictive, an example of dosage effect: foxglove and oleander, foxglove leaf extract. Digitoxigenin: a fairly common heart disease medicine. It jumps starts the heart that beasts irregularly: oleander stem/leaf juice. The (cid:862)(cid:271)ad(cid:863) guy, well k(cid:374)ow(cid:374) to (cid:271)e poiso(cid:374)ous. It contains a chemical that is very similar to digitoxigenin in structure and its effects on humans. Aspirin: chemical was originally extracted from leaves, roots, and flowers of white willow (salix alba)

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