BIO 203 Lecture Notes - Lecture 9: Chemical Synapse, Cell Surface Receptor, Cell Membrane
Document Summary
Ii: action potential lasts till the end of the blue part, graded potential at the red part, depolarization causes ca2+ channels in synaptic membrane to open ca2+ goes into cell. Iii: excitatory: likely to cause graded depolarization in synaptic cell lead to action potential generate. Inhibitory: likely to cause graded hyperpolarization prevent action potential generation. Iv: neurotransmitters returned to axons or transported to glial cells uses energy, can be degraded by enzymes so it can"t bind to receptors & generate action potentials, can diffuse out of cleft. Derivatives of tyrosine: cortisol, enterogastrone, aldosterone, testosterone, dht, estrogen, progesterone, epinephrine, norepinephrine, thyroid hormones, dopamine, serotonin. Insulin: glucagon, acth, crh, anp, adh/avp, angiotensinogen, renin, gastrin, cholecystokinin, secretin, alpha-mullerian. Lh: hcg, gnrh, prolactin, growth hormone, ghrh, comparison of peptide, steroid, amino acid-derived hormones. Modification of existing proteins & induction of new protein synthesis. Activation of genes for transcription & translation. Enhanced secretion when plasma [glucose] <65-70 mg/dl; increased blood amino acids.
