BIO 208 Lecture Notes - Lecture 28: Amygdala, Basal Ganglia, Rodent
19 Sep 2016
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Document Summary
Rewarding brain stimulation: electrical stimulation of the medial forebrain bundle (mfb) is rewarding to mammals. The mfb is a bundle of axons running through the lateral hypothalamus that connect the ventral tegmental area (vta), the nucleus accumbens, and the amygdala: involves dopamine. The ventral tegmental area (vta) contains neurons that make the neurotransmitter dopamine. Axons from the vta project through the medial forebrain bundle (mfb) to a portion of the basal ganglia, the nucleus accumbens. rewarding stimulation could result from dopamine being released into the nucleus accumbens. When rat hears a tone and sees a light, he gets a cue that the lever arm will extend and he can press the lever to receive an electrical stimulus to the medial forebrain bundle. The electrical current produces a release of dopamine in the nucleus accumbens. Electrical stimulation of the medial forebrain bundle causes dopamine release in the nucleus accumbens.
