BIO 361 Lecture Notes - Lecture 26: Amino Sugar, Apicoplast, Lyase
10 Jul 2016
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The krebs cycle is also an important pathway for making intermediates. These pathways are as useful for synthesis as they are for breakdown. It is okay to use the krebs cycle for biosynthesis but that will at a certain point deplete the cell of its opportunities to make high energy intermediates, particularly atp. There are two kinds of reactions that occur that connect the krebs cycle with the rest of the metabolism in the cell. The cataplerotic reactions take intermediates from the krebs cycle and use them for biosynthesis, but they deplete and break down the intermediates of the krebs cycle themselves. The anaplerotic reactions take metabolic intermediates from other pathways and use them to fill up the krebs cycle. The more krebs cycles you can undergo and the more intermediates you have, the more. However, atp synthesis can be compensated for growth.
