PSY 250 Lecture Notes - Lecture 18: Electrophysiology, Aplysia Gill And Siphon Withdrawal Reflex, Habituation

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Neuroplasticity: the brain"s ability to modify synaptic connections as a result of experience. Hebb"s postulate: an increase in synaptic strength arises from the presynaptic cell"s repeated and persistent stimulation of the postsynaptic cell. Hebbian plasticity: if cell a stimulates cell b, the connection becomes stronger. Pavlovian conditioning: before conditioning, the cs does not elicit the response; the. During conditioning, if the cs and ucs are paired during firing, the connection with strengthen. After conditioning, activation of the cs neuron can elicit the salivation response (cr) Summary: if the cs neuron and ucs neuron both fire the cr neuron at the same place and at the same time it causes synaptic changes that allow learning to occur. If food comes before the bell, nothing is learned. Coincidence detection: neurons are able to detect events that happen closely together in time. Coincidence detection by nmda receptors: nmda receptors bind glutamate, nmda receptors are normally blocked by magnesium ions.

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