BIO 211 Lecture Notes - Lecture 5: Resting Potential, Nernst Equation, Tandem Pore Domain Potassium Channel

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24 Mar 2017
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Bio 211 (introduction to neurology: you are a neuroscientist who is studying the factors that affect the resting membrane potential. Currently you are studying neurons whose potassium channel dna are mutated and therefore make fewer k+ leak channels than normal. Negatively charged on the inside and positively charged on the outside of the membrane. Potassium would bring more positive charges wherever it goes: nernst , equilibrium potential for 1 ion, voltage at which # of ions flowing in and out is equal, goldman = K+ will flow with the concentration gradient: ex. How can we find out what the new rmp potential would be: it would be impossible to tell, the goldman equation, the nernst equation, write down the goldman equation. Not c because the starting conditions will be the same, it would take time: tj has been brought into the er unresponsive. Hypothetically, you are able to get a reading on the rmp of her neurons and cardiac cells.

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