BIOL 1001 Lecture Notes - Lecture 12: Exon Skipping, Spliceosome, Microrna
15 Mar 2018
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Document Summary
The promoter regulates where, when, and to what level a gene is expressed. Atg = site for initiation of transcription by rna polymerase. End of atg = site for termination of transcription. Dna to be transcribed unwinds (+ strand of dna) mrna transcript modification. One gene produces several related proteins via splicing. One gene makes 3 different proteins - occurs at a spliceosome complex. Roughly 1. 5% of a person"s genome (exons only) that contains genes for all the proteins produced by the body. Part of the genome formed by exons after introns are removed by rna splicing. Humans have ~21,000 different nuclear genes that encode 20,500 protein genes, 4 ribosomal rna genes, 25 transfer rna genes, and 400 microrna genes. Roughly 180,000 exons constituting about 1% of the total human genome. Virtually all somatic (outside of the sex cells such as sperm and egg cells) cells of your body carry the same genes.
