KINS 1223 Lecture Notes - Lecture 7: Extracellular Fluid, Zipper, Glycocalyx
Document Summary
Glycocalyx: unique fuzzy cell surface, carbohydrate portions of membrane glycoproteins and glycolipids, unique in everyone except identical twins, function, cell recognition, adhesion, and protection. Plasma or cell membrane: sticky surface helps bind adjacent cells together, aids in cellular uptake from extracellular fluid. Id of bacteria and viruses by immune system cells fingerprint. Tight junctions: protein molecules in adjacent plasma membranes fuse together, forms impermeable junction (zipper, prevents passage between cells, example, gi and urinary tract. Desmosomes: protein filaments hold adjacent cells together, plasma membranes do not touch, prevent separation of tissue layers, resists tension forces, most mechanical stress, examples, uterus, heart, epidermis. Gap junctions: connect cells by hollow cylinders composed of transmembrane proteins called connexons, allows small molecules and electrical excitation to pass through connexons, examples, cardiac and smooth muscle. Cytoplasm: organelles, specialized tasks, have a membrane, nucleus, mitochondria, lysosomes, peroxisome, endoplasmic reticulum, and golgi complex, cytosol, clear structureless gel (ifc, cytoskeleton, microfilaments and microtubules.