KINS 1224 Lecture Notes - Lecture 3: Adenylyl Cyclase, Protein Kinase, Inositol
Document Summary
Lectures three: end of endocrine and beginning of cardiovascular. Note: these notes are my transcription of what the professor verbalizes in class and should be used in combination with the power points (which she posts online). Hormone structure/function: hormones can be made from, proteins or amino acids, need receptors (hydrophilic) (will activate the receptors on the surface of the cell, polypeptides: oxytocin, fatty acid or cholesterol, steriod hormones: estrogns and adrogens. Can pass stright through the cell membrane: activate recpetors inside of cell. Protein and peptic: water soluble hormones, peptide, protein, and catecholamines, hydrophilic, transportation, free hormones- floating in blood stream, diffuse through capillary walls. Lipids and cholesterol based hormones: lipid soluble hormones, hydrophobic, transportation, bound hormones, hydrophilic transport proteins. Ie: albumins, globulins: bond breaks at target organ. Secondary messenger systems: hromone binds to the receptor --> signaling cascade --> amplification of signal, two common systems, cyclic adenosine monophosphate (camp, diacylglycero and inositol triphosphate (ip3)