NSG 3336 Lecture Notes - Lecture 27: Vascular Resistance, Pulmonary Hypertension, Pulmonary Artery
Document Summary
Epidemiology > greater risk factor is the presence of dvt. Virchow"s triad = venous stasis, vessel wall damage, and hypercoaguability. Other risk factors = obesity, smoking, chronic heart disease, fracture, hope or knee replacement, major surgery, major trauma, spinal cord injury, history of previous venous thromboembolism, and malignancy. Pathophysiology = when a blood clot or other particulate matter travels to the lungs, it loges in the pulmonary artery and blocks blood ow. Described as decreased blood ow or perfusion = ventilation perfusion mismatch. Prevents gas exchange > hypoxemia (low blood oxygen levels) Increased pulmonary vascular resistance > if right ventricle cant overcome this, the left ventricular preload is reduced = decreased oxygenation, decreased cardiac output, and hypotension. Decreased cardiac output > hypoxia = inadeqaute oxygenation at the cellular level. Pulmonary hypertension may result causing back ow of blood into the right ventricle causing right heart failure.
