BIO-0041 Lecture Notes - Lecture 3: Protein A, Pleiotropy, Zygosity
Document Summary
Complete dominance offspring inherits phenotype of one of the parents (the dominant allele) incomplete dominance hybrid resembles neither parent. Codominance hybrid displays traits of both parents. A = normal allele, pigment production enzyme. Aa pink intermediate phenotype, resembles neither parent. A gene can have more than 2 alleles (a1, a2, a3, ) Dominance relationships are pairwise (a1 vs a2, a1 vs a3, ) Germ line mutations can be transmitted to offspring. Mutations result in phenotypic variants geneticists can follow gene transmission. A2 a2 alive: with 2nd dominant phenotype. A1 is dominant for shiny (in shiny vs wt) but recessive for lethality (in dead vs alive); pairwise dominance. Ay is dominant to a in determining coat color. Ay ay (pure-breeding yellow) dead, impossible to make. Ay a x ay a 2:1 yellow:agouti (1 dead: 2 yellow: 1 agouti) A allele: raly coding region + agouti color coding region. Ay allele: only agouti color coding region.
