BIO 121 Lecture Notes - Lecture 25: Ascending Limb Of Loop Of Henle, Distal Convoluted Tubule, Renal Physiology

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Loop of henle prod high conc gradient within surrounding medullary tissue (countercurrent exchange sys that allows for absorption of water) Absorbing much more fluid urine more conc. than blood (hyperosmotic to it) Has 3 regions: thin descending limb, thin ascending limb, thick ascending limb. Thin descending limb thin ascending limb thick ascending limb distal convoluted tubule collecting ducts. After going through most salts removed & preserved in body & thus left /w urea (major solute) Highly permeable to w. r but not to sodium or chloride. Drawing w. r out of tubule renal filtrate inside limb becomes more conc (high osmolarity) Pump ions out of filtrate & into interstitial fluid. Impermeable to water means ion conc. increases in interstitial fluid. Renal fluid becomes low conc that interstitial fluid. Highly permeable to water & impermeable to ions. Transports urine into ureters which lead to bladder.

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