BIO 121 Lecture Notes - Lecture 12: Carbon Fixation, Inner Membrane, Electrochemical Gradient

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23 Nov 2020
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Structureal and genetic similarities between mitochondria, chloroplasts and. Mito and chloro produced only by binary fission. Cardiolipin is exclusively found in inner mito membrane and bacteria. Proteins in mito/chloro use n-formylmethionine as initiating aa (same as bacteria) Transport proteins called porins found in outer membrane of mitochondria/chloro (same as bacteria) Carry circular dna, similar to size and structure. Proteins encoded are hydrophobic subunits of membrane proteins. Translated on mitochondrial ribosomes and remain in mitochondrion. Parts of transcription/translation machinery (trna, ribosomal proteins, rrna) Large subunit of rubisco involved in carbon fixation. Genomees of mito/chloro are much smaller than genomes of bacteria. Genes lost because function are not needed in intracellular environmentduplicated by nucleus encoded proteins. Other genes of mito/chloro been transfeered to the eukaryotic nucleus. Protein containing signal sequence is synthesized in cytoplasm. Signal sequence binds to receptor on outer mitochondrial membrane.

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