BIO 211 Lecture Notes - Lecture 29: Muscarinic Acetylcholine Receptor, Sympathetic Nervous System, Adrenal Medulla
Document Summary
Sympathetic chain associated with sns: preganglionic axons enter sympathetic chain of ganglia just lateral to spinal cord, usually synapse with postganglionic motor neurons in the chain. Parasympathetic nervous system characteristics: craniosacral division: long pre-ganglionic neurons, short post-ganglionic neurons, pre-ganglionic neurons release ach, bind to nictotinic receptors on post- ganglionic neurons, post- ganglionic releases ach, binds muscarinic receptors on effectors, rest and digest. Adrenal medulla- modified part of sympathetic nervous system. Stimulation of preganglionic fiber prompts secretion of hormones into blood. Classified as either cholinergic or adrenergic neurons based upon the neurotransmitter released. Several different receptor types for postganglionic chemical messengers. Cholinergic receptors- release acetylcholine from pre-ganglionic neurons & from parasympathetic post-ganglionic neurons. Nicotinic receptors- found on postganglionic cell bodies of all autonomic ganglia. Muscarinic receptors- found on effector cell membranes. Andergeneric receptors- release norepinephrine (ne) norepinephrine and epinephrine. Sympathetic: stress or emergencies, tonic activity. Most visceral organs innervated by both sympathetic and parasympathetic fibers.