BIO 211 Lecture Notes - Lecture 16: Nebulin, Myosin Head, Dystrophin
1 Dec 2020
School
Department
Course
Professor
Document Summary
Myofibrils are built of 3 kinds of protein: sarcomere. Each molecule resembles two golf clubs twisted together. Myosin heads extend toward the thin filaments. Structural proteins, e. g. titin, myomesin, nebulin and dystrophin. Myosin thick filaments are composed of myosin. Held in place by the m line proteins. Actin thin filaments are made of actin, troponin and tropomyosin. The myosin-binding site on each actin molecule is covered by tropomyosin in relaxed. The thin filaments are held in place by z lines. From one z line to the next is a. Nebulin elastic protein that helps align the thin filaments. Links thin filaments to sarcolemma and transmits the tension generated to the tendon. Links actin in outermost myofilaments to transmembrane proteins and eventually to. Transfer forces of muscle contraction to connective tissue around muscle cell. Titin giant protein that functions as a molecular spring, which is responsible for the passive. Myosin cross bridges pull on thin filaments.
