BIO 211 Lecture Notes - Lecture 31: Phospholipid, Homeostasis, Osmotic Concentration

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Hydrophobic quality of lipids makes their digestion and absorption more complicated that carbohydrates and proteins. Lipases fat digesting enzymes lingual lipase secreted by the intrinsic salivary glands of the tongue. Active in mouth, but more active in stomach along with gastric lipase. 10-15% of lipids digested before reaches duodenum. Pancreatic lipase in the small intestine digest most of the fats. Fat enters duodenum as large globules exposed to lipase only at their surface. Globules broken up into smaller emulsification droplets by certain components of bile lecithin and bile acids. Absorption of free fatty acids, monoglycerides, and other lipids depends on minute droplets in the bile called micelles (bile salts) Consist of 20 to 40 bile acid molecules aggregated with their hydrophilic side groups facing outward and their hydrophobic steroid rings facing inward. Bile phospholipids and cholesterol diffuse into the center of the micelle to form its core. Micelles pass down the bile duct into the duodenum.

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