BSC 310 Lecture Notes - Lecture 85: Stringent Response, Guanosine Pentaphosphate, Noncoding Dna
30 Mar 2019
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Document Summary
Antibiotics and microbial growth: antibiotics = antimicrobial agents naturally produced by microorganisms; kill or inhibit the growth of bacteria by targeting essential molecular processes, thus, often target enzymes involved with dna replication, rna synthesis, and translation (protein synthesis) Dna replication, and cell division dormancy: this only occurs in cells that randomly produce higher levels of the signal molecule. In prokaryotes, the lack of introns means that their genomes are essentially a series of open reading frames (orfs) If the codon bias in an orf differs greatly from its host"s genome, the orf may be nonfunctional or obtained via lateral gene transfer. Noncoding rna: some genes encode rna molecules that are not translated so lack start codons and may have multiple stop codons. Include things like trnas and rrnas and other molecules that are likely regulatory and conserved only in 3d structure but not sequence homology very hard to identify.
